Description
Human DNA-Directed RNA Polymerase II Subunit RPB2 (POLR2B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DNA-Directed RNA Polymerase II Subunit RPB2 (POLR2B) concentrations in tissue homogenates, cell lysates and other biological fluids. This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]